Point Mutation Variants mapped on to the FXI amino-acid sequence

KEY = FXI DOMAINS: Signal Peptide-- Apple 1-- Apple 2 -- Apple 3 -- Apple 4 --   SP  

MIFLYQVVHF   ILFTSVSGEC   VTQLLKDTCF   EGGDITTVFT   PSAKYCQVVC      50

TYHPRCLLFT   FTAESPSEDP   TRWFTCVLKD   SVTETLPRVN   RTAAISGYSF      100

KQCSHQISAC   NKDIYVDLDM   KGINYNSSVA   KSAQECQERC   TDDVHCHFFT      150

YATRQFPSLE   HRNICLLKHT   QTGTPTRITK   LDKVVSGFSL   KSCALSNLAC      200

IRDIFPNTVF   ADSNIDSVMA   PDAFVCGRIC   THHPGCLFFT   FFSQEWPKES      250

QRNLCLLKTS   ESGLPSTRIK   KSKALSGFSL   QSCRHSIPVF   CHSSFYHDTD      300

FLGEELDIVA   AKSHEACQKL   CTNAVRCQFF   TYTPAQASCN   EGKGKCYLKL      350

SSNGSPTKIL   HGRGGISGYT   LRLCKMDNEC   TTKIKPRIVG   GTASVRGEWP      400

WQVTLHTTSP   TQRHLCGGSI   IGNQWILTAA   HCFYGVESPK   ILRVYSGILN      450

QSEIKEDTSF   FGVQEIIIHD   QYKMAESGYD   IALLKLETTV   NYTDSQRPIC      500

LPSKGDRNVI   YTDCWVTGWG   YRKLRDKIQN   TLQKAKIPLV   TNEECQKRYR      550

GHKITHKMIC   AGYREGGKDA   CKGDSGGPLS   CKHNEVWHLV   GITSWGEGCA      600

QRERPGVYTN   VVEYVDWILE   KTQAV

KEY = FXI DOMAINS: Signal Peptide-- Apple 1-- Apple 2 -- Apple 3 -- Apple 4 --   SP