Protein Structure for Human Coagulation Factor XI

All structural analysis of the missense variants presented within this database uses the FXI structure 2F83 taken from the RCSB Protein Data Bank.
Structure 2F83 consists of a dimer of human FXI (Papagrigoriou et al, Nat Struct Mol Biol 2006 Vol 13(6): 557-558 PMID No 16699514).