Novel FXI Missense Variant Analysis

  • The effects of any undescribed missense variants may be predicted here.
  • Codons are numbered with respect to HGVS nomenclature, with codon 1 representing the first residue (Met) of the signal peptide: type in your codon number of interest.
  • You may select any one option for the "Variant Amino-Acid".

Multiple Sequence Alignment of FXI protein sequence across six Primates    

Note: Clicking and Dragging will take you across the sequence limits
Note: All numbering is for human FXI and is HGVS

FXI HUMAN P03951 | FXI CHIMPANZEE H2QQJ4| FXI GORILLA G3R2X1| FXI GIBBON G1RLE8
FXI MARMOSET F6ZZG6 | FXI BUSHBABY H0WJV6